NATURAL POLYPHENOL BOOSTS MITOCHONDRIAL FUNCTION AND MUSCLE PERFORMANCE DURING AGING
By Vijay Kumar Malesu
Study uncovers a polyphenol's mechanism in enhancing mitochondrial calcium uptake and muscle bioenergetics during aging.
In a recent study published in the Cell Metabolism, a group of researchers explored mitochondrial calcium (mtCa²⁺) uptake in muscle aging and identified oleuropein as a mitochondrial calcium uniporter (MCU) activator to boost energy and performance.
Background
Mitochondrial dysfunction is a key hallmark of aging, contributing to physiological decline and chronic diseases. In skeletal muscle, mtCa²⁺ uptake, regulated by the MCU, plays a vital role in oxidative metabolism and Adenosine trisphosphate (ATP) production during contraction.
2024-12-02T13:38:49Z